mouse ASCL1 shRNA silencing AAV

Name 
AAV-m-ASCL1-shRNA
Cat No 
shAAV-253146
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Ascl1.

shAAV-253146
AAV-m-ASCL1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Ascl1 (achaete-scute family bHLH transcription factor 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
60
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
AI225900; ASH1; bHLHa46; Mash1
Description (Vector)
Transcriptional regulator. May play a role at early stages of development of specific neural lineages in most regions of the CNS, and of several lineages in the PNS. Essential for the generation of olfactory and autonomic neurons. Involved in the initiation of neuronal differentiation. Mediates transcription activation by binding to the E box (5'-CANNTG-3').
Gene ID
17172
Gene Name (Vector)
achaete-scute family bHLH transcription factor 1
Gene Symbol
Ascl1
ORF Size (aa)
696
RefSeq ID
NM_008553
RefSeq Synonyms
NM_008553, BC055748,
Species
mouse
UniGene ID
Mm.136217

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.