mouse ARL6 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Arl6.
shAAV-253023
AAV-m-ARL6-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Arl6 (ADP-ribosylation factor-like 6). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
1110018H24Rik; 2210411E14Rik; BBS3
Description (Vector)
Involved in membrane protein trafficking at the base of the ciliary organelle. Mediates recruitment onto plasma membrane of the BBSome complex which would constitute a coat complex required for sorting of specific membrane proteins to the primary cilia. May regulate cilia assembly and disassembly and subsequent ciliary signaling events such as the Wnt signaling cascade. Isoform 2 may be required for proper retinal function and organization.
Gene ID
56297
Gene Name (Vector)
ADP-ribosylation factor-like 6
Gene Symbol
Arl6
ORF Size (aa)
561
RefSeq ID
NM_019665
RefSeq Synonyms
NM_019665, NM_001347244, BC018497,
Species
mouse
UniGene ID
Mm.392505
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.