mouse ARHGEF7 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Arhgef7.
shAAV-252981
AAV-m-ARHGEF7-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Arhgef7 (Rho guanine nucleotide exchange factor (GEF7)). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
betaPix; betaPix-b; betaPix-c; Cool; cool-1; mKIAA0142; p85Cool1; p85SPR; Pak3bp; PIX
Description (Vector)
Acts as a RAC1 guanine nucleotide exchange factor (GEF) and can induce membrane ruffling. Functions in cell migration, attachment and cell spreading. Promotes targeting of RAC1 to focal adhesions (By similarity). May function as a positive regulator of apoptosis. Downstream of NMDA receptors and CaMKK-CaMK1 signaling cascade, promotes the formation of spines and synapses in hippocampal neurons.
Gene ID
54126
Gene Name (Vector)
Rho guanine nucleotide exchange factor (GEF7)
Gene Symbol
Arhgef7
ORF Size (aa)
1941
ORF Size (bp)
1941 bp
RefSeq ID
NM_017402
RefSeq Synonyms
NM_017402, NM_001113518, NM_001113517, BC044838,
Species
mouse
UniGene ID
Mm.244068
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.