mouse ARHGEF15 shRNA silencing AAV

Name 
AAV-m-ARHGEF15-shRNA
Cat No 
shAAV-252969
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Arhgef15.

shAAV-252969
AAV-m-ARHGEF15-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Arhgef15 (Rho guanine nucleotide exchange factor (GEF) 15). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
D130071N09; D530030K12Rik; E5
Description (Vector)
Specific GEF for RhoA activation. Does not activate RAC1 or CDC42. Regulates vascular smooth muscle contractility. Negatively regulates excitatory synapse development by suppressing the synapse-promoting activity of EPHB2.
Gene ID
442801
Gene Name (Vector)
Rho guanine nucleotide exchange factor (GEF) 15
Gene Symbol
Arhgef15
ORF Size (aa)
2550
ORF Size (bp)
2550 bp
RefSeq ID
NM_177566
RefSeq Synonyms
NM_177566, BC116344, BC116343, BC089365,
Species
mouse
UniGene ID
Mm.376147

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.