mouse ARHGDIG shRNA silencing AAV

Name 
AAV-m-ARHGDIG-shRNA
Cat No 
shAAV-252960
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Arhgdig.

shAAV-252960
AAV-m-ARHGDIG-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Arhgdig (Rho GDP dissociation inhibitor (GDI) gamma). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
Gdi5; Rho-GDI-3; Rho-GDI2; RIP2
Description (Vector)
Inhibits GDP/GTP exchange reaction of RhoB. Interacts specifically with the GDP- and GTP-bound forms of post-translationally processed Rhob and Rhog proteins, both of which show a growth-regulated expression in mammalian cells. Stimulates the release of the GDP-bound but not the GTP-bound RhoB protein. Also inhibits the GDP/GTP exchange of RhoB but shows less ability to inhibit the dissociation of prebound GTP.
Gene ID
14570
Gene Name (Vector)
Rho GDP dissociation inhibitor (GDI) gamma
Gene Symbol
Arhgdig
ORF Size (aa)
678
RefSeq ID
NM_008113
RefSeq Synonyms
NM_008113, BC158003, BC002032,
Species
mouse
UniGene ID
Mm.1383

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.