mouse ARHGAP29 shRNA silencing AAV

Name 
AAV-m-ARHGAP29-shRNA
Cat No 
shAAV-252948
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Arhgap29.

shAAV-252948
AAV-m-ARHGAP29-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Arhgap29 (Rho GTPase activating protein 29). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
6720461J18Rik; A830014I19; AU040217; B130017I01Rik; C76601; Parg1
Description (Vector)
GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. Has strong activity toward RHOA, and weaker activity toward RAC1 and CDC42. May act as a specific effector of RAP2A to regulate Rho. In concert with RASIP1, suppresses RhoA signaling and dampens ROCK and MYH9 activities in endothelial cells and plays an essential role in blood vessel tubulogenesis.
Gene ID
214137
Gene Name (Vector)
Rho GTPase activating protein 29
Gene Symbol
Arhgap29
ORF Size (aa)
3801
ORF Size (bp)
3801 bp
RefSeq ID
NM_172525
RefSeq Synonyms
NM_172525, BC040387,
Species
mouse
UniGene ID
Mm.229287

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.