mouse APLN shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Apln.
shAAV-252822
AAV-m-APLN-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Apln (apelin). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
6030430G11Rik; Apel
Description (Vector)
Endogenous ligand for APJ, an alternative coreceptor with CD4 for HIV-1 infection. Inhibits HIV-1 entry in cells coexpressing CD4 and APJ. Apelin-36 has a greater inhibitory activity on HIV infection than other synthetic apelin derivatives. The oral intake in the colostrum and the milk could have a role in the modulation of the immune responses in neonates. May also have a role in the central control of body fluid homeostasis by influencing AVP release and drinking behavior.
Gene ID
30878
Gene Name (Vector)
apelin
Gene Symbol
Apln
ORF Size (aa)
234
RefSeq ID
NM_013912
RefSeq Synonyms
NM_013912, BC020015,
Species
mouse
UniGene ID
Mm.29262
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.