mouse APAF1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Apaf1.
shAAV-252794
AAV-m-APAF1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Apaf1 (apoptotic peptidase activating factor 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
6230400I06Rik; Apaf-1; Apaf1l; fog; mKIAA0413
Description (Vector)
Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. Isoform 6 is less effective in inducing apoptosis.
Gene ID
11783
Gene Name (Vector)
apoptotic peptidase activating factor 1
Gene Symbol
Apaf1
ORF Size (aa)
3750
ORF Size (bp)
3750 bp
RefSeq ID
NM_009684
RefSeq Synonyms
NM_009684, NM_001282947, NM_001042558, BC131684, BC131683,
Species
mouse
UniGene ID
Mm.220289
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.