mouse AMOT shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Amot.
shAAV-252577
AAV-m-AMOT-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Amot (angiomotin). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CAG-2; D0Kist1; Sii6
Description (Vector)
Plays a central role in tight junction maintenance via the complex formed with ARHGAP17, which acts by regulating the uptake of polarity proteins at tight junctions. Appears to regulate endothelial cell migration and tube formation. May also play a role in the assembly of endothelial cell-cell junctions.
Gene ID
27494
Gene Name (Vector)
angiomotin
Gene Symbol
Amot
ORF Size (aa)
1863
ORF Size (bp)
1863 bp
RefSeq ID
NM_153319
RefSeq Synonyms
NM_153319, NM_001290274, BC057638,
Species
mouse
UniGene ID
Mm.100068
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.