mouse ALKBH8 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Alkbh8.
shAAV-252520
AAV-m-ALKBH8-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Alkbh8 (alkB homolog 8, tRNA methyltransferase). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
4930562C03Rik; 8030431D03Rik; 9430088N01Rik; Abh8
Description (Vector)
Catalyzes the methylation of 5-carboxymethyl uridine to 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in tRNA. Catalyzes the last step in the formation of 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in target tRNA. Has a preference for tRNA(Arg) and tRNA(Glu), and does not bind tRNA(Lys). Required for normal survival after DNA damage. May inhibit apoptosis and promote cell survival and angiogenesis.
Gene ID
67667
Gene Name (Vector)
alkB homolog 8, tRNA methyltransferase
Gene Symbol
Alkbh8
ORF Size (aa)
1995
ORF Size (bp)
1995 bp
RefSeq ID
NM_026303
RefSeq Synonyms
NM_026303, BC050863,
Species
mouse
UniGene ID
Mm.440994
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.