mouse AGK shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Agk.
shAAV-252228
AAV-m-AGK-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Agk (acylglycerol kinase). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
2610037M15Rik; 6720408I04Rik; AI465370; Mulk
Description (Vector)
Lipid kinase that can phosphorylate both monoacylglycerol and diacylglycerol to form lysophosphatidic acid (LPA) and phosphatidic acid (PA), respectively. Does not phosphorylate sphingosine. Overexpression increases the formation and secretion of LPA, resulting in transactivation of EGFR and activation of the downstream MAPK signaling pathway, leading to increased cell growth.
Gene ID
69923
Gene Name (Vector)
acylglycerol kinase
Gene Symbol
Agk
ORF Size (aa)
1266
ORF Size (bp)
1266 bp
RefSeq ID
NM_023538
RefSeq Synonyms
NM_023538, BC093525, BC019145,
Species
mouse
UniGene ID
Mm.32840
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.