mouse AFAP1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Afap1.
shAAV-252197
AAV-m-AFAP1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Afap1 (actin filament associated protein 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
2600003E23Rik; 9630044L16Rik; Afap; AI848729; mKIAA3018
Description (Vector)
Can cross-link actin filaments into both network and bundle structures (By similarity). May modulate changes in actin filament integrity and induce lamellipodia formation. May function as an adapter molecule that links other proteins, such as SRC and PKC to the actin cytoskeleton. Seems to play a role in the development and progression of prostate adenocarcinoma by regulating cell-matrix adhesions and migration in the cancer cells.
Gene ID
70292
Gene Name (Vector)
actin filament associated protein 1
Gene Symbol
Afap1
ORF Size (aa)
2196
ORF Size (bp)
2196 bp
RefSeq ID
NM_027373
RefSeq Synonyms
NM_027373, BC050814,
Species
mouse
UniGene ID
Mm.125167
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.