mouse ADRA1A shRNA silencing AAV

Name
AAV-m-ADRA1A-shRNA

Cat No
shAAV-252163

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Mouse Adra1a.

shAAV-252163

AAV-m-ADRA1A-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Adra1a (adrenergic receptor, alpha 1a). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

Adra1c

Description (Vector)

This alpha-adrenergic receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Its effect is mediated by G(q) and G(11) proteins. Nuclear ADRA1A-ADRA1B heterooligomers regulate phenylephrine(PE)-stimulated ERK signaling in cardiac myocytes.

Gene ID

11549

Gene Name (Vector)

adrenergic receptor, alpha 1a

Gene Symbol

Adra1a

ORF Size (aa)

1401

ORF Size (bp)

1401 bp

RefSeq ID

NM_013461

RefSeq Synonyms

NM_013461, NM_001271761, NM_001271760, NM_001271759, BC113139,

Species

mouse

UniGene ID

Mm.57064

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.