mouse ADAMTS1 shRNA silencing AAV

Name 
AAV-m-ADAMTS1-shRNA
Cat No 
shAAV-252078
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Adamts1.

shAAV-252078
AAV-m-ADAMTS1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Adamts1 (a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
ADAM-TS1; ADAMTS; ADAMTS-1; C3-C5; METH-1; METH1
Description (Vector)
Cleaves aggrecan, a cartilage proteoglycan, and may be involved in its turnover (By similarity). Has angiogenic inhibitor activity. Active metalloprotease, which may be associated with various inflammatory processes as well as development of cancer cachexia. May play a critical role in follicular rupture.
Gene ID
11504
Gene Name (Vector)
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 1
Gene Symbol
Adamts1
ORF Size (aa)
2907
ORF Size (bp)
2907 bp
RefSeq ID
NM_009621
RefSeq Synonyms
NM_009621, BC050834, BC040382,
Species
mouse
UniGene ID
Mm.1421

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.