mouse ACVR1C shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Acvr1c.
shAAV-252020
AAV-m-ACVR1C-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Acvr1c (activin A receptor, type IC). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
ACTR-IC; ACVRLK7; Alk-7; ALK7; C230097P10
Description (Vector)
Serine/threonine protein kinase which forms a receptor complex on ligand binding. The receptor complex consisting of 2 type II and 2 type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators, SMAD2 and SMAD3. Receptor for activin AB, activin B and NODAL. Plays a role in cell differentiation, growth arrest and apoptosis.
Gene ID
269275
Gene Name (Vector)
activin A receptor, type IC
Gene Symbol
Acvr1c
ORF Size (aa)
1092
ORF Size (bp)
1092 bp
RefSeq ID
NM_001111030
RefSeq Synonyms
NM_001111030, NM_001033369, BC160360,
Species
mouse
UniGene ID
Mm.77751
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.