mouse ACE2 shRNA silencing AAV

Name 
AAV-m-ACE2-shRNA
Cat No 
shAAV-251906
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Ace2.

shAAV-251906
AAV-m-ACE2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Ace2 (angiotensin I converting enzyme (peptidyl-dipeptidase A) 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
2010305L05Rik
Description (Vector)
Carboxypeptidase which converts angiotensin I to angiotensin 1-9, a peptide of unknown function, and angiotensin II to angiotensin 1-7, a vasodilator. Also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. May be an important regulator of heart function. In case of human coronaviruses SARS and HCoV-NL63 infections, serve as functional receptor for the spike glycoprotein of both coronaviruses.
Gene ID
70008
Gene Name (Vector)
angiotensin I converting enzyme (peptidyl-dipeptidase A) 2
Gene Symbol
Ace2
ORF Size (aa)
2418
ORF Size (bp)
2418 bp
RefSeq ID
NM_027286
RefSeq Synonyms
NM_027286, NM_001130513, BC026801,
Species
mouse
UniGene ID
Mm.13451

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.