mouse ACE shRNA silencing AAV

Name 
AAV-m-ACE-shRNA
Cat No 
shAAV-251904
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Ace.

shAAV-251904
AAV-m-ACE-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Ace (angiotensin I converting enzyme (peptidyl-dipeptidase A) 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
AW208573; CD143
Description (Vector)
Converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin. Also able to inactivate bradykinin, a potent vasodilator. Has also a glycosidase activity which releases GPI-anchored proteins from the membrane by cleaving the mannose linkage in the GPI moiety.
Gene ID
11421
Gene Name (Vector)
angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
Gene Symbol
Ace
ORF Size (aa)
3939
ORF Size (bp)
3939 bp
RefSeq ID
NM_009598
RefSeq Synonyms
NM_207624, NM_009598, NM_001281819, BC110362, BC040404,
Species
mouse
UniGene ID
Mm.754

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.