mouse AADAC shRNA silencing AAV

Name 
AAV-m-AADAC-shRNA
Cat No 
shAAV-251727
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Aadac.

shAAV-251727
AAV-m-AADAC-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Aadac (arylacetamide deacetylase (esterase)). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
5033417E09Rik; Aada; AI265437
Description (Vector)
Arylacetamide deacetylation is an important enzyme activity in the metabolic activation of arylamine substrates to ultimate carcinogens. Displays major serine hydrolase activity in liver microsomes. Hydrolyzes also flutamide, which is an antiandrogen drug used for the treatment of prostate cancer that occasionaly causes severe hepatotoxicity. Displays cellular triglyceride lipase activity in liver. Increases intracellular fatty acids derived from hydrolysis of newly formed triglyceride stores.
Gene ID
67758
Gene Name (Vector)
arylacetamide deacetylase (esterase)
Gene Symbol
Aadac
ORF Size (aa)
1197
ORF Size (bp)
1197 bp
RefSeq ID
NM_023383
RefSeq Synonyms
NM_023383, BC054823, BC019999,
Species
mouse
UniGene ID
Mm.24547

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.