mouse HJURP shRNA silencing AAV

Name 
AAV-m-HJURP-shRNA
Cat No 
shAAV-251676
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Hjurp.

shAAV-251676
AAV-m-HJURP-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Hjurp (Holliday junction recognition protein). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
50
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
6430706D22Rik; A730008H23Rik; C330011F01Rik; Gm975; Mfleg1
Description (Vector)
Centromeric protein that plays a central role in the incorporation and maintenance of histone H3-like variant CENPA at centromeres. Acts as a specific chaperone for CENPA and is required for the incorporation of newly synthesized CENPA molecules into nucleosomes at replicated centromeres. Prevents CENPA-H4 tetramerization and prevents premature DNA binding by the CENPA-H4 tetramer. Directly binds Holliday junctions.
Gene ID
381280
Gene Name (Vector)
Holliday junction recognition protein
Gene Symbol
Hjurp
ORF Size (aa)
2004
ORF Size (bp)
2004 bp
RefSeq ID
NM_198652
RefSeq Synonyms
NM_198652, BC062125, BC057309,
Species
mouse
UniGene ID
Mm.384762

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.