mouse XRN1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Xrn1.
shAAV-251610
AAV-m-XRN1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Xrn1 (5′-3′ exoribonuclease 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
Dhm2; exo; mXrn1
Description (Vector)
Major 5'-3' exoribonuclease involved in mRNA decay. Required for the 5'-3'-processing of the G4 tetraplex-containing DNA and RNA substrates. The kinetic of hydrolysis is faster for G4 RNA tetraplex than for G4 DNA tetraplex and monomeric RNA tetraplex. Binds to RNA and DNA (By similarity). Plays a role in replication-dependent histone mRNA degradation. May act as a tumor suppressor protein in osteogenic sarcoma (OGS).
Gene ID
24127
Gene Name (Vector)
5'-3' exoribonuclease 1
Gene Symbol
Xrn1
ORF Size (aa)
5172
ORF Size (bp)
5172 bp
RefSeq ID
NM_011916
RefSeq Synonyms
NM_011916, NM_001311130, BC156976, BC156133,
Species
mouse
UniGene ID
Mm.291179
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.