mouse KCNMB4 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Kcnmb4.
shAAV-251557
AAV-m-KCNMB4-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Kcnmb4 (potassium large conductance calcium-activated channel, subfamily M, beta member 4). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
1700058G18Rik; 2900045G12Rik
Description (Vector)
Regulatory subunit of the calcium activated potassium KCNMA1 (maxiK) channel. Modulates the calcium sensitivity and gating kinetics of KCNMA1, thereby contributing to KCNMA1 channel diversity. Decreases the gating kinetics and calcium sensitivity of the KCNMA1 channel, but with fast deactivation kinetics. May decrease KCNMA1 channel openings at low calcium concentrations but increases channel openings at high calcium concentrations. Makes KCNMA1 channel resistant to 100 nM charybdotoxin (CTX) toxin concentrations.
Gene ID
58802
Gene Name (Vector)
potassium large conductance calcium-activated channel, subfamily M, beta member 4
Gene Symbol
Kcnmb4
ORF Size (aa)
633
RefSeq ID
NM_021452
RefSeq Synonyms
NM_021452, BC117779,
Species
mouse
UniGene ID
Mm.440652
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.