mouse 5730590G19RIK shRNA silencing AAV

Name 
AAV-m-5730590G19RIK-shRNA
Cat No 
shAAV-251381
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Ticrr.

shAAV-251381
AAV-m-5730590G19RIK-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Ticrr (TOPBP1-interacting checkpoint and replication regulator). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
5730590G19Rik; BC028450; Lrrk1
Description (Vector)
Regulator of DNA replication and S/M and G2/M checkpoints. Regulates the triggering of DNA replication initiation via its interaction with TOPBP1 by participating in CDK2-mediated loading of CDC45L onto replication origins. Required for the transition from pre-replication complex (pre-RC) to pre-initiation complex (pre-IC). Required to prevent mitotic entry after treatment with ionizing radiation.
Gene ID
77011
Gene Name (Vector)
TOPBP1-interacting checkpoint and replication regulator
Gene Symbol
Ticrr
ORF Size (aa)
5670
ORF Size (bp)
5670 bp
RefSeq ID
NM_029835
RefSeq Synonyms
NM_029835, BC158103,
Species
mouse
UniGene ID
Mm.28132

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.