human FER Over-expression AAV

Name
AAV-h-FER

Cat No
AAV-208901

Availability
4-5 weeks

This is an AAV expressing Human FER.

AAV-208901

AAV-h-FER

Ready-to-use AAV expressing Human FER (FER tyrosine kinase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

feline encephalitis virus-related kinase FER; fer (fps/fes related) tyrosine kinase; fujinami poultry sarcoma/Feline sarcoma-related protein Fer; p94-Fer; phosphoprotein NCP94; PPP1R74; protein phosphatase 1, regulatory subunit 74; proto-oncogene c-Fer; TYK3; tyrosine kinase 3; tyrosine-protein kinase Fer

Description (eCommerce)

Feline encephalitis virus-related kinase (FER) is a member of the FPS/FES family of nontransmembrane receptor tyrosine kinases. It regulates cell-cell adhesion and mediates signaling from the cell surface to the cytoskeleton via growth factor receptors [taken from NCBI Entrez Gene (Gene ID: 2241)].

Description (Vector)

Fer protein is a member of the FPS/FES family of nontransmembrane receptor tyrosine kinases. It regulates cell-cell adhesion and mediates signaling from the cell surface to the cytoskeleton via growth factor receptors.

Gene ID

2241

Gene Name (eCommerce)

FER tyrosine kinase

Gene Name (Vector)

FER tyrosine kinase

Gene Symbol

FER

HGNC ID

HGNC:3655

NCBI Taxonomy ID (eCommerce)

9606.0

ORF Size (aa)

2466

ORF Size (bp)

2466 bp

Protein Name (eCommerce)

Tyrosine-protein kinase Fer

RefSeq ID

NM_005246

RefSeq Synonyms

NM_005246, NM_001308038, NM_001308031, NM_001308028, BC141559,

Research Areas

Breast Cancer,Cancer,Cell Cycle,Cytoskeleton,Fc Receptor Signaling,Immunology,Insulin Signaling,Interleukin Signaling,Kinase/Phosphatase,SCF-KIT Signaling,Signal Transduction,T-cell Receptor Signaling

Research Areas (Faceted)

cancer,cell_biology,cell_cycle,genetics,immunology,signal_transduction,stem_cell_biology

Species

human

Target Sentence

Feline encephalitis virus-related kinase (FER) is a member of the FPS/FES family of nontransmembrane receptor tyrosine kinases. It regulates cell-cell adhesion and mediates signaling from the cell surface to the cytoskeleton via growth factor receptors [taken from NCBI Entrez Gene (Gene ID: 2241)].

UniGene ID

Hs.221472

UniProt ID (eCommerce)

P16591

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.