human FECH Over-expression AAV

Name
AAV-h-FECH

Cat No
AAV-208895

Availability
4-5 weeks

This is an AAV expressing Human FECH.

AAV-208895

AAV-h-FECH

Ready-to-use AAV expressing Human FECH (ferrochelatase). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

EPP; FCE

Description (Vector)

FECH is localized to the mitochondrion, where it catalyzes the insertion of the ferrous form of iron into protoporphyrin IX in the heme synthesis pathway. Mutations in this gene are associated with erythropoietic protoporphyria. Two transcript variants encoding different isoforms have been found for this gene. A pseudogene of this gene is found on chromosome 3.

Gene ID

2235

Gene Name (Vector)

ferrochelatase

Gene Symbol

FECH

HGNC ID

HGNC:3647

ORF Size (aa)

1272

ORF Size (bp)

1272 bp

RefSeq ID

NM_000140

RefSeq Synonyms

NM_001012515, NM_000140, BC039841,

Species

human

UniGene ID

Hs.365365

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.