mouse 1110054O05RIK shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Inip.
shAAV-250157
AAV-m-1110054O05RIK-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Inip (INTS3 and NABP interacting protein). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
1110054O05Rik; 2610312O17Rik; AA399876; Ssbip1
Description (Vector)
Component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint. The SOSS complex associates with single-stranded DNA at DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintenance of genomic stability. Required for efficient homologous recombination-dependent repair of double-strand breaks (DSBs) and ATM-dependent signaling pathways.
Gene ID
66209
Gene Name (Vector)
INTS3 and NABP interacting protein
Gene Symbol
Inip
ORF Size (aa)
315
RefSeq ID
NM_001013577
RefSeq Synonyms
NM_001013577, BC116205, BC116204,
Species
mouse
UniGene ID
Mm.443220
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.