human WDR3 shRNA silencing AAV

Name 
AAV-h-WDR3-shRNA
Cat No 
shAAV-234048
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human WDR3.

shAAV-234048
AAV-h-WDR3-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human WDR3 (WD repeat domain 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
DIP2; dJ776P7.2 (WD repeat domain 3); UTP12; WD repeat-containing protein 3
Description (eCommerce)
WDR3 (WD repeat containing protein 3) is a member of the WD protein family. The WD repeat is defined by four or more repeating units of a conserved core of approximately 40 amino acids ending with tryptophan-aspartic acid (WD). WD repeats may serve as sites of protein-protein interaction for adaptor proteins and facilitate multiprotein complex formation. WD proteins are involved in a variety of cellular processes. The function of WDR3 has not been characterized.
Description (Vector)
WDR3 encodes a nuclear protein containing 10 WD repeats. WD repeats are approximately 30- to 40-amino acid domains containing several conserved residues, which usually include a trp-asp at the C-terminal end. Proteins belonging to the WD repeat family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation.
Gene ID
10885
Gene Name (eCommerce)
WD repeat domain 3
Gene Name (Vector)
WD repeat domain 3
Gene Symbol
WDR3
HGNC ID
HGNC:12755
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
123
Protein Name (eCommerce)
WD repeat-containing protein 3
RefSeq ID
NM_006784
RefSeq Synonyms
NM_006784, BC058836,
Research Areas
Cell Biology,Translational Control
Research Areas (Faceted)
cell_biology,transcription_translation
Species
human
Target Sentence
WDR3 (WD repeat containing protein 3) is a member of the WD protein family. The WD repeat is defined by four or more repeating units of a conserved core of approximately 40 amino acids ending with tryptophan-aspartic acid (WD). WD repeats may serve as sites of protein-protein interaction for adaptor proteins and facilitate multiprotein complex formation. WD proteins are involved in a variety of cellular processes. The function of WDR3 has not been characterized.
UniProt ID (eCommerce)
Q9UNX4

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.