human HIST1H1C shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human HIST1H1C.
shAAV-233814
AAV-h-HIST1H1C-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human HIST1H1C (histone cluster 1 H1 family member c). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
H1.2; H1C; H1F2; H1s-1
Description (Vector)
Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H1 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6.
Gene ID
3006
Gene Name (Vector)
histone cluster 1 H1 family member c
Gene Symbol
HIST1H1C
HGNC ID
HGNC:4716
ORF Size (aa)
642
RefSeq ID
NM_005319
RefSeq Synonyms
NM_005319, BC002649,
Species
human
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.