human FBXW12 Over-expression AAV

Name 
AAV-h-FBXW12
Cat No 
AAV-208831
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human FBXW12.

AAV-208831
AAV-h-FBXW12

Ready-to-use AAV expressing Human FBXW12 (F-box and WD repeat domain containing 12). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
FBW12; FBXO12; FBXO35
Description (Vector)
Members of the F-box protein family, such as FBXW12, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603034), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 (PubMed 15520277)).(supplied by OMIM, Mar 2008)
Gene ID
285231
Gene Name (Vector)
F-box and WD repeat domain containing 12
Gene Symbol
FBXW12
HGNC ID
HGNC:20729
ORF Size (aa)
789
RefSeq ID
NM_207102
RefSeq Synonyms
NM_207102, NM_001159929, NM_001159927, BC101305, BC101304, BC101303,
Species
human
UniGene ID
Hs.288793

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.