human PLEKHG2 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human PLEKHG2.
shAAV-232804
AAV-h-PLEKHG2-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human PLEKHG2 (pleckstrin homology and RhoGEF domain containing G2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
ARHGEF42; CLG; common-site lymphoma/leukemia guanine nucleotide exchange factor; CTB-60E11.4; LDAMD; PH domain-containing family G member 2; pleckstrin homology domain containing, family G (with RhoGef domain) member 2; pleckstrin homology domain-containing family G member 2
Description (eCommerce)
PLEKHG2 (pleckstrin homology domain-containing family G member 2) contains a RhoGEF/DH domain and a pleckstrin homology (PH) domain. PH domains are found in proteins involved in cell signaling. PLEKHG2 is proposed to be a guanine-nucleotide exchange factor (GEF) for RAC1/CDC42.
Gene ID
64857
Gene Name (eCommerce)
pleckstrin homology and RhoGEF domain containing G2
Gene Name (Vector)
pleckstrin homology and RhoGEF domain containing G2
Gene Symbol
PLEKHG2
HGNC ID
HGNC:29515
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2977
ORF Size (bp)
2977 bp
Protein Name (eCommerce)
Pleckstrin homology domain-containing family G member 2
RefSeq ID
NM_022835
RefSeq Synonyms
NM_022835, BC013426,
Research Areas
Apoptosis,Cancer,GPCR Signaling,Neurobiology,NGF Signaling,Rho Signaling,Signal Transduction,Tumor Suppressors/Oncoproteins
Research Areas (Faceted)
cancer,cell_biology,neurobiology,signal_transduction
Species
human
Target Sentence
PLEKHG2 (pleckstrin homology domain-containing family G member 2) contains a RhoGEF/DH domain and a pleckstrin homology (PH) domain. PH domains are found in proteins involved in cell signaling. PLEKHG2 is proposed to be a guanine-nucleotide exchange factor (GEF) for RAC1/CDC42.
UniProt ID (eCommerce)
Q9H7P9
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.