human VPS16 shRNA silencing AAV

Name
AAV-h-VPS16-shRNA

Cat No
shAAV-232126

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human VPS16.

shAAV-232126

AAV-h-VPS16-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human VPS16 (VPS16, CORVET/HOPS core subunit). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

hVPS16

Description (Vector)

Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene encodes the human homolog of yeast class C Vps16 protein. The mammalian class C Vps proteins are predominantly associated with late endosomes/lysosomes, and like their yeast counterparts, may mediate vesicle trafficking steps in the endosome/lysosome pathway. Two transcript variants encoding different isoforms have been found for this gene.

Gene ID

64601

Gene Name (Vector)

VPS16, CORVET/HOPS core subunit

Gene Symbol

VPS16

HGNC ID

HGNC:14584

ORF Size (aa)

1575

ORF Size (bp)

1575 bp

RefSeq ID

NM_022575

RefSeq Synonyms

NM_080413, NM_022575, BC073959,

Species

human

UniGene ID

Hs.

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.