human QSOX1 shRNA silencing AAV

Name
AAV-h-QSOX1-shRNA

Cat No
shAAV-231760

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human QSOX1.

shAAV-231760

AAV-h-QSOX1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human QSOX1 (quiescin sulfhydryl oxidase 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

Q6; QSCN6

Description (Vector)

QSOX1 encodes a protein that contains domains of thioredoxin and ERV1, members of two long-standing gene families. The gene expression is induced as fibroblasts begin to exit the proliferative cycle and enter quiescence, suggesting that this gene plays an important role in growth regulation. Two transcript variants encoding two different isoforms have been found for this gene.

Gene ID

5768

Gene Name (Vector)

quiescin sulfhydryl oxidase 1

Gene Symbol

QSOX1

HGNC ID

HGNC:9756

ORF Size (aa)

2244

ORF Size (bp)

2244 bp

RefSeq ID

NM_001004128

RefSeq Synonyms

NM_002826, NM_001004128, BC100023, BC017692,

Species

human

UniGene ID

Hs.719176

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.