human GTF3C6 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human GTF3C6.
shAAV-230636
AAV-h-GTF3C6-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human GTF3C6 (general transcription factor IIIC subunit 6). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
bA397G5.3; C6orf51; TFIIIC35
Description (Vector)
RNA polymerases are unable to initiate RNA synthesis in the absence of additional proteins called general transcription factors (GTFs). GTFs assemble in a complex on the DNA promoter and recruit the RNA polymerase. GTF3C family proteins (e.g., GTF3C1, MIM 603246) are essential for RNA polymerase III to make a number of small nuclear and cytoplasmic RNAs, including 5S RNA (MIM 180420), tRNA, and adenovirus-associated (VA) RNA of both cellular and viral origin.(supplied by OMIM, Mar 2008)
Gene ID
112495
Gene Name (Vector)
general transcription factor IIIC subunit 6
Gene Symbol
GTF3C6
HGNC ID
HGNC:20872
ORF Size (aa)
642
RefSeq ID
NM_138408
RefSeq Synonyms
NM_138408, BC011593,
Species
human
UniGene ID
Hs.418520
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.