human GUCA1B shRNA silencing AAV

Name 
AAV-h-GUCA1B-shRNA
Cat No 
shAAV-230596
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human GUCA1B.

shAAV-230596
AAV-h-GUCA1B-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human GUCA1B (guanylate cyclase activator 1B). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
GCAP2; GUCA2; RP48
Description (Vector)
GUCA1B is a calcium-binding protein that activates photoreceptor guanylate cyclases. This gene may have arisen due to a gene duplication event since there is a highly similar gene clustered with it on chromosome 6. Mutations in this gene can cause a form of retinitis pigmentosa.
Gene ID
2979
Gene Name (Vector)
guanylate cyclase activator 1B
Gene Symbol
GUCA1B
HGNC ID
HGNC:4679
ORF Size (aa)
603
RefSeq ID
NM_002098
RefSeq Synonyms
NM_002098, BC166640,
Species
human
UniGene ID
Hs.446529

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.