human LIPT1 shRNA silencing AAV

Name
AAV-h-LIPT1-shRNA

Cat No
shAAV-230071

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human LIPT1.

shAAV-230071

AAV-h-LIPT1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human LIPT1 (lipoyltransferase 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

LIPT1D

Description (Vector)

The process of transferring lipoic acid to proteins is a two-step process. The first step is the activation of lipoic acid by lipoate-activating enzyme to form lipoyl-AMP. For the second step, the protein encoded by this gene transfers the lipoyl moiety to apoproteins. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 13. Read-through transcription also exists between this gene and the neighboring downstream mitochondrial ribosomal protein L30 (MRPL30) gene.

Gene ID

51601

Gene Name (Vector)

lipoyltransferase 1

Gene Symbol

LIPT1

HGNC ID

HGNC:29569

ORF Size (aa)

1122

RefSeq ID

NM_015929

RefSeq Synonyms

NM_145199, NM_145198, NM_145197, NM_015929, NM_001204830, BC070145, BC009772, BC007001,

Species

human

UniGene ID

Hs.

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.