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human PI4K2B shRNA silencing AAV

Name 
AAV-h-PI4K2B-shRNA
Cat No 
shAAV-229442
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human PI4K2B.

shAAV-229442
AAV-h-PI4K2B-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human PI4K2B (phosphatidylinositol 4-kinase type 2 beta). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
PI4KIIB; PIK42B
Description (Vector)
Phosphatidylinositol 4-kinases (PI4Ks) phosphorylate phosphatidylinositol to generate phosphatidylinositol 4-phosphate (PIP), an immediate precursor of several important signaling and scaffolding molecules. PIP itself may also have direct functional and structural roles. PI4K2B is a primarily cytosolic PI4K that is recruited to membranes, where it stimulates phosphatidylinositol 4,5-bisphosphate synthesis (Wei et al., 2002 (PubMed 12324459)).(supplied by OMIM, Jun 2008)
Gene ID
55300
Gene Name (Vector)
phosphatidylinositol 4-kinase type 2 beta
Gene Symbol
PI4K2B
HGNC ID
HGNC:18215
ORF Size (aa)
1446
ORF Size (bp)
1446 bp
RefSeq ID
NM_018323
RefSeq Synonyms
NM_018323, BC051749,
Species
human
UniGene ID
Hs.191701

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.