human ZNRF1 shRNA silencing AAV

Name 
AAV-h-ZNRF1-shRNA
Cat No 
shAAV-228965
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human ZNRF1.

shAAV-228965
AAV-h-ZNRF1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human ZNRF1 (zinc and ring finger 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
NIN283
Description (Vector)
ZNRF1 encodes an E3 ubiquitin-protein ligase that plays a role in neural-cell differentiation. Overexpression of this gene causes neurite-like elongation. The encoded protein contains both a zinc finger and a RING finger motif and is localized in the endosome/lysosome compartment, indicating that it may be involved in ubiquitin-mediated protein modification, and in synaptic vessicle membranes in neurons.
Gene ID
84937
Gene Name (Vector)
zinc and ring finger 1
Gene Symbol
ZNRF1
HGNC ID
HGNC:18452
ORF Size (aa)
684
RefSeq ID
NM_032268
RefSeq Synonyms
NM_032268, BC007235,
Species
human
UniGene ID
Hs.427284

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.