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human ZNF598 shRNA silencing AAV

Name 
AAV-h-ZNF598-shRNA
Cat No 
shAAV-228725
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human ZNF598.

shAAV-228725
AAV-h-ZNF598-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human ZNF598 (zinc finger protein 598). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
E3 ubiquitin-protein ligase ZNF598; HEL2; Zinc finger protein 598
Description (eCommerce)
Zinc-finger proteins bind nucleic acids and play important roles in various cellular functions, including cell proliferation, differentiation, and apoptosis. The protein encoded by the gene ZNF598, Zinc Finger Protein 598, and Grb10-interacting GYF protein 2 have been identified as a components of the mammalian 4EHP (m4EHP) complex. The complex is thought to function as a translation repressor in embryonic development [taken from NCBI Entrez Gene (Gene ID: 90850)].
Gene ID
90850
Gene Name (eCommerce)
zinc finger protein 598
Gene Name (Vector)
zinc finger protein 598
Gene Symbol
ZNF598
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2715
ORF Size (bp)
2715 bp
Protein Name (eCommerce)
Zinc finger protein 598
RefSeq ID
NM_178167
RefSeq Synonyms
NM_178167, BC050477,
Research Areas
Zinc-finger
Research Areas (Faceted)
cell_biology
Species
human
Target Sentence
Zinc-finger proteins bind nucleic acids and play important roles in various cellular functions, including cell proliferation, differentiation, and apoptosis. The protein encoded by the gene ZNF598, Zinc Finger Protein 598, and Grb10-interacting GYF protein 2 have been identified as a components of the mammalian 4EHP (m4EHP) complex. The complex is thought to function as a translation repressor in embryonic development [taken from NCBI Entrez Gene (Gene ID: 90850)].
UniGene ID
Hs.343828
UniProt ID (eCommerce)
Q86UK7

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.