human ZFP36L1 shRNA silencing AAV

Name
AAV-h-ZFP36L1-shRNA

Cat No
shAAV-228212

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human ZFP36L1.

shAAV-228212

AAV-h-ZFP36L1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human ZFP36L1 (ZFP36 ring finger protein like 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

Berg36; BRF1; cMG1; ERF-1; ERF1; RNF162B; TIS11B

Description (Vector)

ZFP36L1 is a member of the TIS11 family of early response genes, which are induced by various agonists such as the phorbol ester TPA and the polypeptide mitogen EGF. ZFP36L1 is well conserved across species and has a promoter that contains motifs seen in other early-response genes. The encoded protein contains a distinguishing putative zinc finger domain with a repeating cys-his motif. This putative nuclear transcription factor most likely functions in regulating the response to growth factors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene ID

677

Gene Name (Vector)

ZFP36 ring finger protein like 1

Gene Symbol

ZFP36L1

HGNC ID

HGNC:1107

ORF Size (aa)

1017

RefSeq ID

NM_004926

RefSeq Synonyms

NM_004926, NM_001244701, NM_001244698, BC018340,

Species

human

UniGene ID

Hs.707091

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.