human ZBP1 shRNA silencing AAV

Name
AAV-h-ZBP1-shRNA

Cat No
shAAV-228040

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human ZBP1.

shAAV-228040

AAV-h-ZBP1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human ZBP1 (Z-DNA binding protein 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

C20orf183; DAI; DLM-1; DLM1

Description (Vector)

ZBP1 encodes a Z-DNA binding protein. The encoded protein plays a role in the innate immune response by binding to foreign DNA and inducing type-I interferon production. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Gene ID

81030

Gene Name (Vector)

Z-DNA binding protein 1

Gene Symbol

ZBP1

HGNC ID

HGNC:16176

ORF Size (aa)

1290

RefSeq ID

NM_030776

RefSeq Synonyms

NM_030776, NM_001323966, NM_001160419, NM_001160418, NM_001160417, BC131706,

Species

human

UniGene ID

Hs.302123

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.