human YTHDC1 shRNA silencing AAV

Name
AAV-h-YTHDC1-shRNA

Cat No
shAAV-227995

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human YTHDC1.

shAAV-227995

AAV-h-YTHDC1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human YTHDC1 (YTH domain containing 1). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

70

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

putative splicing factor YT521; splicing factor YT521; splicing factor YT521-B; YT521; YT521-B; YTH domain-containing protein 1

Description (eCommerce)

YTH domain-containing protein 1, encoded by the gene YTHDC1, specifically recognizes and binds N6-methyladenosine (m6A)-containing RNAs and regulates alternative splice site selection [taken from UniProtKB (Entry: Q96MU7)].

Gene ID

91746

Gene Name (eCommerce)

YTH domain containing 1

Gene Name (Vector)

YTH domain containing 1

Gene Symbol

YTHDC1

NCBI Taxonomy ID (eCommerce)

9606.0

ORF Size (aa)

2184

ORF Size (bp)

2184 bp

Protein Name (eCommerce)

YTH domain-containing protein 1

RefSeq ID

NM_133370

RefSeq Synonyms

NM_133370, NM_001330698, NM_001031732, BC053863, BC041119,

Research Areas

Gene Expression,mRNA Processing,mRNA Splicing,RNA Binding,RNA Processing

Research Areas (Faceted)

cell_biology,genetics,transcription_translation

Species

human

Target Sentence

YTH domain-containing protein 1, encoded by the gene YTHDC1, specifically recognizes and binds N6-methyladenosine (m6A)-containing RNAs and regulates alternative splice site selection [taken from UniProtKB (Entry: Q96MU7)].

UniGene ID

Hs.175955

UniProt ID (eCommerce)

Q96MU7

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.