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human XYLT1 shRNA silencing AAV

Name 
AAV-h-XYLT1-shRNA
Cat No 
shAAV-227941
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human XYLT1.

shAAV-227941
AAV-h-XYLT1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human XYLT1 (xylosyltransferase 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
DBQD2; PXYLT1; XT-I; XT1; XTI; xylT-I; XYLTI
Description (Vector)
This locus encodes a xylosyltransferase enzyme. The encoded protein catalyzes transfer of UDP-xylose to serine residues of an acceptor protein substrate. This transfer reaction is necessary for biosynthesis of glycosaminoglycan chains. Mutations in this gene have been associated with increased severity of pseudoxanthoma elasticum.
Gene ID
64131
Gene Name (Vector)
xylosyltransferase 1
Gene Symbol
XYLT1
HGNC ID
HGNC:15516
ORF Size (aa)
2877
ORF Size (bp)
2877 bp
RefSeq ID
NM_022166
RefSeq Synonyms
NM_022166, BC156039,
Species
human
UniGene ID
Hs.610023

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.