human WNT6 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human WNT6.
shAAV-227834
AAV-h-WNT6-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human WNT6 (Wnt family member 6). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Description (Vector)
The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It is overexpressed in cervical cancer cell line and strongly coexpressed with another family member, WNT10A, in colorectal cancer cell line. The gene overexpression may play key roles in carcinogenesis. This gene and the WNT10A gene are clustered in the chromosome 2q35 region. The protein encoded by this gene is 97% identical to the mouse Wnt6 protein at the amino acid level.
Gene ID
7475
Gene Name (Vector)
Wnt family member 6
Gene Symbol
WNT6
HGNC ID
HGNC:12785
ORF Size (aa)
1098
RefSeq ID
NM_006522
RefSeq Synonyms
NM_006522, BC004329,
Species
human
UniGene ID
Hs.29764
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.