human WBSCR22 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human WBSCR22.
shAAV-227628
AAV-h-WBSCR22-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human WBSCR22 (Williams-Beuren syndrome chromosome region 22). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
HASJ4442; HUSSY-3; MERM1; PP3381; WBMT
Description (Vector)
WBSCR22 encodes a protein containing a nuclear localization signal and an S-adenosyl-L-methionine binding motif typical of methyltransferases, suggesting that the encoded protein may act on DNA methylation. WBSCR22 is deleted in Williams syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at 7q11.23. Alternatively spliced transcript variants have been found.
Gene ID
114049
Gene Name (Vector)
Williams-Beuren syndrome chromosome region 22
Gene Symbol
WBSCR22
HGNC ID
HGNC:16405
ORF Size (aa)
846
RefSeq ID
NM_017528
RefSeq Synonyms
NM_017528, NM_001202560, BC011696, BC001780, BC000169,
Species
human
UniGene ID
Hs.647063
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.