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human WASF2 shRNA silencing AAV

Name 
AAV-h-WASF2-shRNA
Cat No 
shAAV-227598
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human WASF2.

shAAV-227598
AAV-h-WASF2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human WASF2 (WAS protein family member 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
dJ393P12.2; IMD2; SCAR2; WASF4; WAVE2
Description (Vector)
WASF2 encodes a member of the Wiskott-Aldrich syndrome protein family. The gene product is a protein that forms a multiprotein complex that links receptor kinases and actin. Binding to actin occurs through a C-terminal verprolin homology domain in all family members. The multiprotein complex serves to tranduce signals that involve changes in cell shape, motility or function. The published map location (PMID:10381382) has been changed based on recent genomic sequence comparisons, which indicate that the expressed gene is located on chromosome 1, and a pseudogene may be located on chromosome X. Two transcript variants encoding different isoforms have been found for this gene.
Gene ID
10163
Gene Name (Vector)
WAS protein family member 2
Gene Symbol
WASF2
HGNC ID
HGNC:12733
ORF Size (aa)
1497
ORF Size (bp)
1497 bp
RefSeq ID
NM_006990
RefSeq Synonyms
NM_006990, NM_001201404, BC040943,
Species
human
UniGene ID
Hs.590909

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.