human VPS28 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human VPS28.
shAAV-227522
AAV-h-VPS28-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human VPS28 (VPS28, ESCRT-I subunit). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Description (Vector)
VPS28 encodes a protein involved in endosomal sorting of cell surface receptors via a multivesicular body/late endosome pathway. The encoded protein is one of the three subunits of the ESCRT-I complex (endosomal complexes required for transport) involved in the sorting of ubiquitinated proteins. The two other subunits of ESCRT-I are vesicular protein sorting 23, also known as tumor susceptibility gene 101 (TSG101), and vesicular protein sorting 37. Two alternative transcripts encoding different isoforms have been described. Additional alternative transcripts may exist but the proteins encoded by these transcripts have not been verified experimentally.
Gene ID
51160
Gene Name (Vector)
VPS28, ESCRT-I subunit
Gene Symbol
VPS28
HGNC ID
HGNC:18178
ORF Size (aa)
702
RefSeq ID
NM_016208
RefSeq Synonyms
NM_183057, NM_016208, BC050713, BC019321, BC006485,
Species
human
UniGene ID
Hs.418175
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.