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human VDAC2 shRNA silencing AAV

Name 
AAV-h-VDAC2-shRNA
Cat No 
shAAV-227452
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human VDAC2.

shAAV-227452
AAV-h-VDAC2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human VDAC2 (voltage dependent anion channel 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
POR
Description (Vector)
VDAC2 encodes a member of the voltage-dependent anion channel pore-forming family of proteins that are considered the main pathway for metabolite diffusion across the mitochondrial outer membrane. The encoded protein is also thought to be involved in the mitochondrial apoptotic pathway via regulation of BCL2-antagonist/killer 1 protein activity. Pseudogenes have been identified on chromosomes 1, 2, 12 and 21, and alternative splicing results in multiple transcript variants.
Gene ID
7417
Gene Name (Vector)
voltage dependent anion channel 2
Gene Symbol
VDAC2
HGNC ID
HGNC:12672
ORF Size (aa)
885
RefSeq ID
NM_003375
RefSeq Synonyms
NM_003375, NM_001324090, NM_001324089, NM_001324088, NM_001324087, NM_001184823, NM_001184783, BC072407, BC012883, BC000165,
Species
human
UniGene ID
Hs.355927

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.