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human VAT1 shRNA silencing AAV

Name 
AAV-h-VAT1-shRNA
Cat No 
shAAV-227407
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human VAT1.

shAAV-227407
AAV-h-VAT1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human VAT1 (vesicle amine transport 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
membrane protein of cholinergic synaptic vesicles; synaptic vesicle membrane protein VAT-1 homolog; VATI; vesicle amine transport protein 1 homolog (T. californica)
Description (eCommerce)
Vesicle amine transport 1 (VAT1) is an abundant integral membrane protein of cholinergic synaptic vesicles and is thought to be involved in vesicular transport. It belongs to the quinone oxidoreductase subfamily of zinc-containing alcohol dehydrogenase proteins [taken from NCBI Entrez Gene (Gene ID: 10493)].
Description (Vector)
Synaptic vesicles are responsible for regulating the storage and release of neurotransmitters in the nerve terminal. The protein encoded by this gene is an abundant integral membrane protein of cholinergic synaptic vesicles and is thought to be involved in vesicular transport. It belongs to the quinone oxidoreductase subfamily of zinc-containing alcohol dehydrogenase proteins.
Gene ID
10493
Gene Name (eCommerce)
vesicle amine transport 1
Gene Name (Vector)
vesicle amine transport 1
Gene Symbol
VAT1
HGNC ID
HGNC:16919
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1182
ORF Size (bp)
1182 bp
Protein Name (eCommerce)
Synaptic vesicle membrane protein VAT-1 homolog
RefSeq ID
NM_006373
RefSeq Synonyms
NM_006373, BC090858, BC015041, BC014279, BC008725,
Research Areas
Mitochondrion
Research Areas (Faceted)
cell_biology
Species
human
Target Sentence
Vesicle amine transport 1 (VAT1) is an abundant integral membrane protein of cholinergic synaptic vesicles and is thought to be involved in vesicular transport. It belongs to the quinone oxidoreductase subfamily of zinc-containing alcohol dehydrogenase proteins [taken from NCBI Entrez Gene (Gene ID: 10493)].
UniGene ID
Hs.514199
UniProt ID (eCommerce)
Q99536

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.