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human UQCRC2 shRNA silencing AAV

Name 
AAV-h-UQCRC2-shRNA
Cat No 
shAAV-227247
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human UQCRC2.

shAAV-227247
AAV-h-UQCRC2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human UQCRC2 (ubiquinol-cytochrome c reductase core protein II). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
complex III subunit 2; Core protein II; cytochrome bc-1 complex core protein II; cytochrome b-c1 complex subunit 2, mitochondrial; MC3DN5; QCR2; ubiquinol-cytochrome c reductase core protein II; ubiquinol-cytochrome-c reductase complex core protein 2; UQCR2
Description (eCommerce)
Ubiquinol-cytochrome-c reductase complex core protein 2 (UQCRC2) is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. The core protein 2 is required for the assembly of the complex [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P22695].
Gene ID
7385
Gene Name (eCommerce)
ubiquinol-cytochrome c reductase core protein 2
Gene Name (Vector)
ubiquinol-cytochrome c reductase core protein II
Gene Symbol
UQCRC2
HGNC ID
HGNC:12586
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1362
ORF Size (bp)
1362 bp
Protein Name (eCommerce)
Cytochrome b-c1 complex subunit 2, mitochondrial
RefSeq ID
NM_003366
RefSeq Synonyms
NM_003366, BC003136, BC000484,
Research Areas
Alzheimer's Disease,Cardiology,Cardiovascular,Huntington's Disease,Metabolism/Metabolic Process,Mitochondrion,Neurobiology,Neurodegeneration,Parkinson's Disease
Research Areas (Faceted)
neurobiology,cardiovascular,metabolism,cell_biology
Species
human
Target Sentence
Ubiquinol-cytochrome-c reductase complex core protein 2 (UQCRC2) is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. The core protein 2 is required for the assembly of the complex [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P22695].
UniGene ID
Hs.528803
UniProt ID (eCommerce)
P22695

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.