human UQCC shRNA silencing AAV

Name 
AAV-h-UQCC-shRNA
Cat No 
shAAV-227240
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human UQCC1.

shAAV-227240
AAV-h-UQCC-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human UQCC1 (ubiquinol-cytochrome c reductase complex assembly factor 1). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
basic FGF-repressed Zic-binding protein; bFGF-repressed Zic-binding protein; BFZB; C20orf44; CBP3; cytochrome B protein synthesis 3 homolog; ubiquinol-cytochrome c reductase complex chaperone CBP3 homolog; ubiquinol-cytochrome-c reductase complex assembly factor 1; UQCC
Description (eCommerce)
UQCC1 is a transmembrane protein that is structurally similar to the mouse basic fibroblast growth factor repressed ZIC-binding protein. In mouse this protein may be involved in fibroblast growth factor regulated growth control. In humans, polymorphisms in this gene are associated with variation in human height and osteoarthritis [taken from NCBI Entrez Gene (Gene ID: 55245)].
Description (Vector)
UQCC encodes a transmembrane protein that is structurally similar to the mouse basic fibroblast growth factor repressed ZIC-binding protein. In mouse this protein may be involved in fibroblast growth factor regulated growth control. In humans, polymorphisms in this gene are associated with variation in human height and osteoarthritis. Alternate splicing results in multiple transcript variants.
Gene ID
55245
Gene Name (eCommerce)
ubiquinol-cytochrome c reductase complex assembly factor 1
Gene Name (Vector)
ubiquinol-cytochrome c reductase complex assembly factor 1
Gene Symbol
UQCC1
HGNC ID
HGNC:15891
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
900
Protein Name (eCommerce)
Ubiquinol-cytochrome-c reductase complex assembly factor 1
RefSeq ID
NM_018244
RefSeq Synonyms
NM_199487, NM_018244, NM_001184977, BC122862, BC119013, BC105791, BC008871,
Research Areas
Mitochondrion
Research Areas (Faceted)
cell_biology
Species
human
Target Sentence
UQCC1 is a transmembrane protein that is structurally similar to the mouse basic fibroblast growth factor repressed ZIC-binding protein. In mouse this protein may be involved in fibroblast growth factor regulated growth control. In humans, polymorphisms in this gene are associated with variation in human height and osteoarthritis [taken from NCBI Entrez Gene (Gene ID: 55245)].
UniGene ID
Hs.714359
UniProt ID (eCommerce)
Q9NVA1

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.