human UPK2 shRNA silencing AAV

Name
AAV-h-UPK2-shRNA

Cat No
shAAV-227231

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human UPK2.

shAAV-227231

AAV-h-UPK2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human UPK2 (uroplakin 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

UP2; UPII

Description (Vector)

UPK2 encodes one of the proteins of the highly conserved urothelium-specific integral membrane proteins of the asymmetric unit membrane which forms urothelium apical plaques in mammals. The asymmetric unit membrane is believed to strengthen the urothelium by preventing cell rupture during bladder distention. The encoded protein is expressed in the peripheral blood of bladder cancer patients with transitional cell carcinomas.

Gene ID

7379

Gene Name (Vector)

uroplakin 2

Gene Symbol

UPK2

HGNC ID

HGNC:12579

ORF Size (aa)

555

RefSeq ID

NM_006760

RefSeq Synonyms

NM_006760, BC113900,

Species

human

UniGene ID

Hs.710330

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.